Use the following answers to the conversations to unlock the best ending for that person:
Zeke Sanders Empathize, Empathize, Empathize, Empathize. Zeke will release the hostage and flee. If you let Zeke leave but make a mistake in the rest of the conversation, he will still go but the hostage will die.
Wayne Haas Absolve, Absolve, Absolve/Plead, Crush. This givesyou unrestricted access to the non-restricted areas of the Detroit police station. Note: This unlocks the "Desk Job" achievement.
David Sarif Refocus, Refocus, Refocus, Defend. David will give you emails and records about Adam's past and the security loophole. Note: This unlocks the "Yes Boss" achievement.
Tong Si Hung Pinpoint, Advise, Pinpoint. Adam can go downstairs to meet with the Triad leader that owns The Hive. Note: This unlocks the "Darker Shades" achievement.
Bill Taggart Confront, Discredit, Confront, Discredit. Bill Taggart gives you the location of Dr. Isaias Sandoval. Note: This unlocks the "Throwdown" achievement.
Doctor Isaias Sandoval Tough Love, Empathize, Empathize. This prevents Isaias Sandoval from killing themself. Note: This unlocks the "Last Straw" achievement.
Hugh Darrow Extrapolate, Extrapolate, Appeal, Extrapolate/Appeal. Hugh Darrow deactivates the security system and you will get the code to shut down the Hyron system. Note: This unlocks the "Final Countdown" achievement.