Complete the game, then start a new game with the cleared saved game file to start with the following bonuses:
-Choose your Loyalty Bonus Skill from the start. -Retain Skill Points but can redistribute them. -Retain level and XP carry over; the max level is 30. -+25% experience bonus for all characters -Renegade/Paragon points are reset to neutral. -Retain weapons and armor, but not the upgrades.