Perform the following steps to easily defeat the final boss:

Part 1
Use Empower to get through his shield. Then use the Panzer Rocket Launcher and the Veil Blue Rocket Launcher.

Part 2
Use Slow Motion or Empower.

Part3
Instead of running up the ramp, snipe him with a sniper rifle orrocket launcher. When you are about to climb the stairs, have a weaponequipped to kill the 4 legged sniffers. Then shoot him until he falls.

Part 4
He will now have no power ups. Continue to shoot him and use explosives to kill him.